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Caz
  • Caz
  • Advanced Member
18 May 2020 13:24:05


Asymptomatic people can later test positive for antibodies. I did post a story earlier from Camden in north London of 5 teachers who are taking part in a study and have antibodies despite not having reported any symptoms


http://camdennewjournal.com/article/virus-may-have-already-swept-through-school-in-spring


Originally Posted by: JHutch 

Thanks!  I hadn’t seen that but it’s interesting!  That also begs the question we’ve also debated, whether the virus was more widely spread earlier than we think.  Although Darren’s antibody testing was negative and partly debunked that idea but as keyworkers are being antibody tested now, or some time soon, it will perhaps shed more light. 

Market Warsop, North Nottinghamshire.
Join the fun and banter of the monthly CET competition.
Gavin D
18 May 2020 13:26:11

The 122 hospital deaths in England by date



  • 27 on May 17th

  • 59 on May 16th

  • 29 on May 15th

  • 6 on May 14th

  • 1 on May 13th

Gavin D
18 May 2020 13:27:13
Spain are hoping to allow Brits to travel to the country without needing to isolate upon arrival from the end of June

speckledjim
18 May 2020 13:29:32


 


You wont be glad if you catch it thanks to Boris's reckless attitude


 


 


Originally Posted by: The Beast from the East 


Don’t believe Boris is being remotely reckless and I’m content with the risk to me. May have already had it anyway and been asymptomatic.

Thorner, West Yorkshire


Journalism is organised gossip
Gavin D
18 May 2020 13:30:06

​


 Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials




Quote

 


The Oxford University vaccine, tipped as a “front runner” in the race to develop a coronavirus jab, does not stop the virus in monkeys and may only be partially effective, experts have warned. A trial of the vaccine in rhesus macaque monkeys did not stop the animals from catching the virus and has raised questions about the vaccine’s likely human efficacy and ongoing development. The vaccine, known as ChAdOx1 nCoV-19, is now undergoing human trials in Britain. The Government has brokered a deal between Oxford University and AstraZeneca, the drug company, to produce up to 30 million doses if it proves successful having ploughed £47m into the research.


“All of the vaccinated monkeys treated with the Oxford vaccine became infected when challenged as judged by recovery of virus genomic RNA from nasal secretions,” said Dr William Haseltine, a former Harvard Medical School professor who had a pivotal role in the development of early HIV/Aids treatments. “There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected,” he wrote in an article on Forbes. Jonathan Ball, professor of molecular virology at the University of Nottingham, said that the vaccine data suggests that the jab may not be able to prevent the spread of the virus between infected individuals. 


“That viral loads in the noses of vaccinated and unvaccinated animals were identical is very significant. If the same happened in humans, vaccination would not stop spread,” he said.  “I genuinely believe that this finding should warrant an urgent re-appraisal of the ongoing human trials of the ChAdOx1 vaccine.” The trials investigated the immune response to the Oxford vaccine in rhesus macaque monkeys and were carried out at the National Institute of Health’s Rocky Mountain Laboratory in the US, with initial results published in a press release at the end of April. 


 





https://www.telegraph.co.uk/global-health/science-and-disease/doubts-oxford-vaccine-fails-stop-coronavirus-animal-trials/


​

Caz
  • Caz
  • Advanced Member
18 May 2020 13:34:28

All 122 hospital deaths reported today in England were within the last 5-days

Originally Posted by: Gavin D 

Gavin, is there a graph showing daily positive tests?

Market Warsop, North Nottinghamshire.
Join the fun and banter of the monthly CET competition.
Retron
18 May 2020 13:37:43


Gavin, is there a graph showing daily positive tests?


Originally Posted by: Caz 


https://www.worldometers.info/coronavirus/country/uk/


 

Leysdown, north Kent
Gavin D
18 May 2020 13:39:42


Gavin, is there a graph showing daily positive tests?


Originally Posted by: Caz 


 


Every week day from 5pm on BBC News/Sky News or from 4pm on weekends they show that graph.

Caz
  • Caz
  • Advanced Member
18 May 2020 13:40:46


https://www.worldometers.info/coronavirus/country/uk/


 

Originally Posted by: Retron 

Ahh!  Thanks Darren!  

Market Warsop, North Nottinghamshire.
Join the fun and banter of the monthly CET competition.
Joe Bloggs
18 May 2020 13:44:30


​


 Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials




Quote

 


The Oxford University vaccine, tipped as a “front runner” in the race to develop a coronavirus jab, does not stop the virus in monkeys and may only be partially effective, experts have warned. A trial of the vaccine in rhesus macaque monkeys did not stop the animals from catching the virus and has raised questions about the vaccine’s likely human efficacy and ongoing development. The vaccine, known as ChAdOx1 nCoV-19, is now undergoing human trials in Britain. The Government has brokered a deal between Oxford University and AstraZeneca, the drug company, to produce up to 30 million doses if it proves successful having ploughed £47m into the research.


“All of the vaccinated monkeys treated with the Oxford vaccine became infected when challenged as judged by recovery of virus genomic RNA from nasal secretions,” said Dr William Haseltine, a former Harvard Medical School professor who had a pivotal role in the development of early HIV/Aids treatments. “There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected,” he wrote in an article on Forbes. Jonathan Ball, professor of molecular virology at the University of Nottingham, said that the vaccine data suggests that the jab may not be able to prevent the spread of the virus between infected individuals. 


“That viral loads in the noses of vaccinated and unvaccinated animals were identical is very significant. If the same happened in humans, vaccination would not stop spread,” he said.  “I genuinely believe that this finding should warrant an urgent re-appraisal of the ongoing human trials of the ChAdOx1 vaccine.” The trials investigated the immune response to the Oxford vaccine in rhesus macaque monkeys and were carried out at the National Institute of Health’s Rocky Mountain Laboratory in the US, with initial results published in a press release at the end of April. 


 





https://www.telegraph.co.uk/global-health/science-and-disease/doubts-oxford-vaccine-fails-stop-coronavirus-animal-trials/


​


Originally Posted by: Gavin D 


https://www.nytimes.com/2020/04/27/world/europe/coronavirus-vaccine-update-oxford.html


I'll read both articles later to see what has changed. 


Manchester City Centre, 31m ASL
ozone_aurora
18 May 2020 13:46:15


 


You can sign a petition for what its worth


 




Originally Posted by: The Beast from the East 


Signed it! 

Call for a new thread on this?

Maunder Minimum
18 May 2020 13:47:35


 


Don’t believe Boris is being remotely reckless and I’m content with the risk to me. May have already had it anyway and been asymptomatic.


Originally Posted by: speckledjim 


Beast is just a troll who posts whatever comes into his head at the time - only a few weeks ago he was railing against pub closures.


Anyhow, I would rather face the risk of COVID personally, than spend the next few weeks stuck at home.


People are too risk averse these days - it is one thing to take sensible precautions (as I do) and another to stay at home like some namby-pamby. All this nonsense about visiting beaches and parks, the safest places to be, provided you keep sufficient distance from others that they don't cough all over you.


 

New world order coming.
Tim A
18 May 2020 13:50:06


 


https://www.nytimes.com/2020/04/27/world/europe/coronavirus-vaccine-update-oxford.html


I'll read both articles later to see what has changed. 


Originally Posted by: Joe Bloggs 


 


From my recollection of the positive story the other day, the vaccine may:


 


Reduce infection within the lungs and severity of symptoms. But not on its presence in the nose/throat.


So people who are vaccinated are more likely to have weak symptoms but can still pass it on.


 


Not ideal , but better than nothing?


 


Will be interesting to see whether countries rush for a suboptimal vaccine or hold out for a more effective one.


 


 

Tim
NW Leeds
187m asl

 My PWS 
The Beast from the East
18 May 2020 13:52:05


 


I think Harries said the infection rate is likely to be half of its current value when schools reopen in a couple of weeks. 


Originally Posted by: Brian Gaze 


She also said it was safe for the Liverpool/Madrid game and Cheltenham to go ahead 


Yet, no journalist seems to be ask her about this. There is video of her saying it!

Purley, Surrey, 70m ASL

"We have some alternative facts for you"

Kelly-Ann Conway - former special adviser to the President
John p
18 May 2020 13:52:22


​


 Doubts over Oxford vaccine as it fails to stop coronavirus in animal trials




Quote

 


The Oxford University vaccine, tipped as a “front runner” in the race to develop a coronavirus jab, does not stop the virus in monkeys and may only be partially effective, experts have warned. A trial of the vaccine in rhesus macaque monkeys did not stop the animals from catching the virus and has raised questions about the vaccine’s likely human efficacy and ongoing development. The vaccine, known as ChAdOx1 nCoV-19, is now undergoing human trials in Britain. The Government has brokered a deal between Oxford University and AstraZeneca, the drug company, to produce up to 30 million doses if it proves successful having ploughed £47m into the research.


“All of the vaccinated monkeys treated with the Oxford vaccine became infected when challenged as judged by recovery of virus genomic RNA from nasal secretions,” said Dr William Haseltine, a former Harvard Medical School professor who had a pivotal role in the development of early HIV/Aids treatments. “There was no difference in the amount of viral RNA detected from this site in the vaccinated monkeys as compared to the unvaccinated animals. Which is to say, all vaccinated animals were infected,” he wrote in an article on Forbes. Jonathan Ball, professor of molecular virology at the University of Nottingham, said that the vaccine data suggests that the jab may not be able to prevent the spread of the virus between infected individuals. 


“That viral loads in the noses of vaccinated and unvaccinated animals were identical is very significant. If the same happened in humans, vaccination would not stop spread,” he said.  “I genuinely believe that this finding should warrant an urgent re-appraisal of the ongoing human trials of the ChAdOx1 vaccine.” The trials investigated the immune response to the Oxford vaccine in rhesus macaque monkeys and were carried out at the National Institute of Health’s Rocky Mountain Laboratory in the US, with initial results published in a press release at the end of April. 


 





https://www.telegraph.co.uk/global-health/science-and-disease/doubts-oxford-vaccine-fails-stop-coronavirus-animal-trials/


​


Originally Posted by: Gavin D 


The actual pre print document says it seems to not prevent transmission, but does prevent pneumonia developing. 
I wonder if it also blocks the myriad other ailments I’ve seen reported? Kidneys, blood clots etc ?


Also a note to the Telegraph 


Preprint: "should not be reported in news media as established information"


😉

Camberley, Surrey
The Beast from the East
18 May 2020 13:57:43


 


The uptick at the end, following a stagnation, is indeed worrying - all being equal, it would suggest R is hovering around or just above 1, which obviously isn't good!


This is also very similar to the pattern of the number of new cases being detected, which has also plateaued at about 3500 a day.


This would suggest that if anything the restrictions should be tightened again, unless we're happy to have that many cases around (it's far higher than France, Spain, Italy etc).


100-150 a day in terms of deaths might be optimistic, at least outside of the lower totals reported on Sunday and Monday due to the weekend...


 


Originally Posted by: Retron 


It was idiotic to relax lockdown before a track and trace programme was in place. Ours still wont be ready for weeks and its been outsourced to the private sector who will no doubt be using work experience kids.


In other countries, the tracers are experienced professionals who know the local community and are trusted by local people. That's the only way you get people to comply and reveal their true contacts


This is another HMG clusterfuck

Purley, Surrey, 70m ASL

"We have some alternative facts for you"

Kelly-Ann Conway - former special adviser to the President
The Beast from the East
18 May 2020 14:01:04


 


 


 


Not ideal , but better than nothing?


 


Will be interesting to see whether countries rush for a suboptimal vaccine or hold out for a more effective one.


 


 


Originally Posted by: Tim A 


Yes, but would you want to get it, if you could wait for a better one? Can you get both?


 

Purley, Surrey, 70m ASL

"We have some alternative facts for you"

Kelly-Ann Conway - former special adviser to the President
fairweather
18 May 2020 14:01:22


 


Don’t believe Boris is being remotely reckless and I’m content with the risk to me. May have already had it anyway and been asymptomatic.


Originally Posted by: speckledjim 


I get fed up with these me me me posts. Never a thought or understanding about transmission rate to the vulnerable.

S.Essex, 42m ASL
The Beast from the East
18 May 2020 14:05:30


 


Beast is just a troll who posts whatever comes into his head at the time - only a few weeks ago he was railing against pub closures.


Anyhow, I would rather face the risk of COVID personally, than spend the next few weeks stuck at home.


People are too risk averse these days - it is one thing to take sensible precautions (as I do) and another to stay at home like some namby-pamby. All this nonsense about visiting beaches and parks, the safest places to be, provided you keep sufficient distance from others that they don't cough all over you.


 


Originally Posted by: Maunder Minimum 


If you end up in Hospital, I'll read this out to you

Purley, Surrey, 70m ASL

"We have some alternative facts for you"

Kelly-Ann Conway - former special adviser to the President
springsunshine
18 May 2020 14:17:05


 


Beast is just a troll who posts whatever comes into his head at the time - only a few weeks ago he was railing against pub closures.


Anyhow, I would rather face the risk of COVID personally, than spend the next few weeks stuck at home.


People are too risk averse these days - it is one thing to take sensible precautions (as I do) and another to stay at home like some namby-pamby. All this nonsense about visiting beaches and parks, the safest places to be, provided you keep sufficient distance from others that they don't cough all over you.


 


Originally Posted by: Maunder Minimum 


Get outside and enjoy the glorious weather and all those on furlough make the bloody most of this extended time off as it won`t happen again until you retire!! Iam out fishing pretty much every other day now and absolutely loving not having to go to work The chances of catching the virus outside are slim to none as long as you are sensible and careful. My motto is out of adversity comes opportunity.

Maunder Minimum
18 May 2020 14:19:23


 


If you end up in Hospital, I'll read this out to you


Originally Posted by: The Beast from the East 


If I end up in hospital, you will be the first to know Beast. Meanwhile, I am just getting on with life and not worrying too much about the random chance of catching a bug.


In the old days, TB, Typhoid, Diphtheria and a host of other communicable diseases were present in all communities, but people still got on with their lives.

New world order coming.
Retron
18 May 2020 14:19:34


 That's the only way you get people to comply and reveal their true contacts


Originally Posted by: The Beast from the East 


How far does the tracing go, I wonder?


For example, imagine this scenario:


I go back to work in the school and come down with flu-like symtoms. I get tested and find I've got it.


On my way into work the previous day (when I'd have been shedding the virus), I stopped off at the bakery and the petrol station, nipping in to get some basic supplies. On the way back, realising I'd forgotten to buy a birthday card for a friend, I popped into Tesco, queuing for 10 minutes to get in. It was busy in there and I had to queue again at the checkout.


How many of those people I'd have been involved with would get traced? Very few, I suspect!

Leysdown, north Kent
Maunder Minimum
18 May 2020 14:22:45


 


Get outside and enjoy the glorious weather and all those on furlough make the bloody most of this extended time off as it won`t happen again until you retire!! Iam out fishing pretty much every other day now and absolutely loving not having to go to work The chances of catching the virus outside are slim to none as long as you are sensible and careful. My motto is out of adversity comes opportunity.


Originally Posted by: springsunshine 


That's the spirit!

New world order coming.
Phil G
18 May 2020 14:24:37


 


Get outside and enjoy the glorious weather and all those on furlough make the bloody most of this extended time off as it won`t happen again until you retire!! Iam out fishing pretty much every other day now and absolutely loving not having to go to work The chances of catching the virus outside are slim to none as long as you are sensible and careful. My motto is out of adversity comes opportunity.


Originally Posted by: springsunshine 


Post of the day!

speckledjim
18 May 2020 14:28:40


 


I get fed up with these me me me posts. Never a thought or understanding about transmission rate to the vulnerable.


Originally Posted by: fairweather 


If you want to hide away until we get a vaccine then be my guest. I am taking no unnecessary risks and am following government guidelines. I am the only one in my household that goes to a shop and I make every effort to keep my distance. I don’t work and my wife is working from home. I have 2 daughters and am now allowing them to see one friend at a time. If that’s me being self centred then so be it, I’ll continue to sleep easily at night.

Thorner, West Yorkshire


Journalism is organised gossip

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