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Gavin D
12 March 2020 20:50:38
Anyone who becomes ill within the UK and hasn't had confirmed direct contact with someone already infected you will no longer be tested and should not phone 111.

You instead have to self isolate and only call 111 if you don't improve after 7-day's

https://www.gov.uk/government/publications/covid-19-stay-at-home-guidance/stay-at-home-guidance-for-people-with-confirmed-or-possible-coronavirus-covid-19-infection 

Chunky Pea
12 March 2020 20:53:08


 


The imponderable question is how long will it take to develop and test an effective vaccine and have it available for mass (and I mean mass - hundreds of millions)  use?


When it comes to herd immunity, it really does depend on the bug - for example:


"To achieve herd immunity for measles at least 90-95% of the population need to be vaccinated. A disease like polio is less contagious, and 80-85% of the population would need to be vaccinated for herd immunity to work."


Since COVID-19 is in the highly contagious category, you are looking at 90% plus for herd immunity, either by people having it and getting antibodies by fighting it off, or via an effective vaccine.


Originally Posted by: Maunder Minimum 


Whatever about 'herd immunity', one thing Euro Governments need to publicly advocate against is the increase in herd mentality. 


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"You don't have to know anything to have an opinion"
--Roger P, 12/Oct/2022
Devonian
12 March 2020 20:56:48

Several hundred thousand people die every year in normal times.


And, while full herd immunity might need 80% plus of us to get it, is it the case the more people who have immunity the slower it will spread until it gradually stops? I wonder what the % is to get it to slow? Well, if 50% have immunity it has to spread more slowly (err, does it? I've actually no idea, it's a question for modellers) than if no one has immunity?

Polar Low
12 March 2020 20:59:04

Hello Ben good news is most virus mutations are of negative value of the virus and the same vaccine can be used rather than explain I came across this a bit of a long read but interesting as the other day I wondered myself.


https://www.livescience.com/coronavirus-mutations.html


 


 



 


Pretty much everyone. We have to manage the severe cases through the health system without going through those spikes that would stress the NHS too much so that those that need acute care can get it when they need it. That's the policy outlined by UK GOV IMO, and I agree with it as the best way forward.


I'm not worried by comparisons to other countries, but the caveat is there's much that is not known about this virus. It may be something that rears it's head again in those that have already had it with further complications, without of course considering the shift that may occur once a vaccine is widely available and used. Of course if we've all had it, we might not need a vaccine, but that doesn't stop a mutation in other countries where they apply the vaccine.


At the end of the day, it's a bit of a gamble, but a gamble made on science rather than sentiment.


Originally Posted by: Arcus 

Gavin D
12 March 2020 21:00:41

Lockdowns now starting in Spain


 


 



Bugglesgate
12 March 2020 21:03:14


I read a lot of support for the approach the government is taking. That's fair enough but is anyone making an attempt to quantify what it means in terms of deaths? Are we talking about hundreds, thousands, tens of thousands, hundreds of thousands or millions in the UK? I agree that economic cost is an important consideration but the benchmark must be the body count.


Originally Posted by: Brian Gaze 


 


I think deaths are "nailed on" no matter what approach we take


I instinctively like the UK Gov. approach becuase it takes a hit in the shorter term for a better long term outlook.


The 2 things that can go wrong though are :-



  1. Exponential growth and a overwhelmed  NHS  leading to a massive  death rate.

  2. We  suffer a  lot of deaths but don't achieve the immunity desired and get clobbered a 2nd time.


The policy of containment may work if a vaccine is developed before the 2nd wave strikes.  If   a vaccine is still a year away  (which most people say it is) then those in the containment lobby will have virtually a full flu  season to endure in addition to  this year.  The chances of maintaining containment throughout that entire 2nd period must be slim and containment failure may be worse if teh 2nd wave is more virulent than the first (people seem to think this is likley from the Spanish Flu precedent)


 


 


Chris (It,its)
Between Newbury and Basingstoke
"When they are giving you their all, some stagger and fall, after all it's not easy banging your heart against some mad buggers wall"
xioni2
12 March 2020 21:06:57


I think whatever approach we take, the mortality rate will be the same. 


Originally Posted by: Caz 


That is clearly wrong as demonstrated by other countries and it goes completely against what the WHO is recommending.


I find the UK approach to be extremely risky and I worry that we'll end up one of the worst countries in Europe.


 

xioni2
12 March 2020 21:09:53


The UK government is not alone in its approach - Holland has a remarkably similar strategy:



  • A ban on gatherings of more than 100 people


Originally Posted by: Maunder Minimum 


How can you call the 2 approaches similar given the point above?


Gandalf The White
12 March 2020 21:09:54


 


So we're aiming at about 500,000 Brit civilian deaths if Whitty is right about mortality being a tad under 1%. About 8x as many as Hitler managed. If the dude from Hong Kong is right with 1.4% then we ratchet that up towards 3/4 million. If that is the best strategy available I shudder to think of the alternatives. 


Originally Posted by: Brian Gaze 


Peehaps the missing part of the equation is the number of cases being missed because the symptoms are so mild. The CMO said five to ten times as many could be infected as have actually been identified.  If it's the top figure and the illness is mild then 1% becomes 0.1%  - still not good but maybe with a vaccine after the first wave it becomes an understandable strategy?


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Maunder Minimum
12 March 2020 21:10:53

Interesting stats:


https://www.medrxiv.org/content/10.1101/2020.03.09.20033217v1


"Here, we investigate the stability of viable HCoV-19 on surfaces and in aerosols in comparison with SARS-CoV-1. Overall, stability is very similar between HCoV-19 and SARS-CoV-1. We found that viable virus could be detected in aerosols up to 3 hours post aerosolization, up to 4 hours on copper, up to 24 hours on cardboard and up to 2-3 days on plastic and stainless steel. HCoV-19 and SARS-CoV-1 exhibited similar half-lives in aerosols, with median estimates around 2.7 hours. Both viruses show relatively long viability on stainless steel and polypropylene compared to copper or cardboard: the median half-life estimate for HCoV-19 is around 13 hours on steel and around 16 hours on polypropylene. Our results indicate that aerosol and fomite transmission of HCoV-19 is plausible, as the virus can remain viable in aerosols for multiple hours and on surfaces up to days."


New world order coming.
xioni2
12 March 2020 21:18:15

Went to my local pizza express tonight and it was almost deserted, the manager said they are seeing already a big impact.


 

Maunder Minimum
12 March 2020 21:19:28


 


How can you call the 2 approaches similar given the point above?



Originally Posted by: xioni2 


That is more or less the one point of difference.


New world order coming.
Polar Low
12 March 2020 21:20:05

Not likely if you read this


But most of these mutations negatively affect the virus. If mutations are not beneficial to the virus, they are typically eliminated through natural selection, the mechanism of evolution whereby organisms better adapted to their environment tend to survive. Other mutations survive and get embedded into the "average" genome of a virus.


Typically, multiple genes code for traits such as a virus's severity or ability to transmit to other people, Grubaugh wrote. So, for a virus to become more severe or transmit more easily, multiple genes would have to mutate. Despite high rates of mutation among viruses in general, it's unusual to find viruses that change their mode of transmission between humans over such short time scales, he wrote.


So, what does all of this mean for the development of a possible vaccine? 


These viruses "are still so genetically similar that these mutations shouldn't alter a new vaccine," Grubaugh said. It's "unlikely that the developers have to worry about this." Once the vaccine is out, however, the virus could adapt to it and develop resistance, he said, but considering that other RNA viruses — such as those that cause measles, mumps and yellow fever — didn't develop resistance to vaccines, that scenario is unlikely.


https://www.livescience.com/coronavirus-mutations.html


 


 



 


 


I think deaths are "nailed on" no matter what approach we take


I instinctively like the UK Gov. approach becuase it takes a hit in the shorter term for a better long term outlook.


The 2 things that can go wrong though are :-



  1. Exponential growth and a overwhelmed  NHS  leading to a massive  death rate.

  2. We  suffer a  lot of deaths but don't achieve the immunity desired and get clobbered a 2nd time.


The policy of containment may work if a vaccine is developed before the 2nd wave strikes.  If   a vaccine is still a year away  (which most people say it is) then those in the containment lobby will have virtually a full flu  season to endure in addition to  this year.  The chances of maintaining containment throughout that entire 2nd period must be slim and containment failure may be worse if teh 2nd wave is more virulent than the first (people seem to think this is likley from the Spanish Flu precedent)


 


 


Originally Posted by: Bugglesgate 

Gavin D
12 March 2020 21:20:38

xioni2
12 March 2020 21:20:51


 That is more or less the one point of difference.


Originally Posted by: Maunder Minimum 


Which makes the 2 approaches quite different? Lots of events with more than 100 people!


 

nsrobins
12 March 2020 21:25:49

Without being too melodramatic, we are facing a level of distress and loss not seen since WW2. Families will lose loved ones before their time, and the collective resolve of communities will be tested to the limit in the next few months. I suspect we will emerge from this episode with a whole new perspective on our lives and how we approach crises like this in the future.
I have an elderly mother whose respiratory state is to say the least compromised. She lives in a home with 34 equally elderly people in close proximity. Suffice to say we will do all we can to isolate her and minimise her chances of infection, but reading between the lines I fear the worst case scenario is inevitable.
I’m probably not the only one this evening re-evaluating what my priorities are at the moment and I will be spending quite a bit of time with her at the weekend - taking all possible precautions of course.


Neil
Fareham, Hampshire 28m ASL (near estuary)
Stormchaser, Member TORRO
Brian Gaze
12 March 2020 21:29:18


Went to my local pizza express tonight and it was almost deserted, the manager said they are seeing already a big impact.


 


Originally Posted by: xioni2 


A number of the booked seats on the flight back from Helsinki today were empty. I suspect a number of people bailed out at the last minute partly because of Trump's announcement.  


Brian Gaze
Berkhamsted
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"I'm not socialist, I know that. I don't believe in sharing my money." - Gary Numan
Devonian
12 March 2020 21:30:24


 


Peehaps the missing part of the equation is the number of cases being missed because the symptoms are so mild. The CMO said five to ten times as many could be infected as have actually been identified.  If it's the top figure and the illness is mild then 1% becomes 0.1%  - still not good but maybe with a vaccine after the first wave it becomes an understandable strategy?


Originally Posted by: Gandalf The White 


Raises interesting questions.


What would be the mortality if, say, measles was introduced to 70million unvaccinated people who'd never encountered it? Many would show no disease, or a mild illness, but a number of people would die - I think the reaction might well be like we see now. Which reminds me of what European diseases did to native south Americans... This virus does not seem to be in that category!


Otoh, do some people get flu and not show symptoms?

Brian Gaze
12 March 2020 21:36:08

Another question is what should you do if you contract it?


Presumably drink lots of water. I also assume eating as well as possible is advisable. More uncertain are things like cough medicine, aspirin, nurofen, paracetamol, codeine, nytol etc. I've not seen official guidance on off the shelf medicines such as these.


Brian Gaze
Berkhamsted
TWO Buzz - get the latest news and views 
"I'm not socialist, I know that. I don't believe in sharing my money." - Gary Numan
Joe Bloggs
12 March 2020 21:36:42

Actual footage of my work place next week. I guarantee it. 


https://www.instagram.com/p/B9pbj0EANOb/?igshid=x2wgie9r1cx3


 



Manchester City Centre, 31m ASL

Polar Low
12 March 2020 21:38:18

You don’t want measles had that as a young lad was really sick as a parrot with it as was my sister.


 



 


Raises interesting questions.


What would be the mortality if, say, measles was introduced to 70million unvaccinated people who'd never encountered it? Many would show no disease, or a mild illness, but a number of people would die. Which reminds me of what European diseases did to native south Americans... This virus does not seem to be in that category!


Otoh, do some people get flu and not show symptoms?


Originally Posted by: Devonian 

xioni2
12 March 2020 21:40:00


Actual footage of my work place next week. I guarantee it. 
https://www.instagram.com/p/B9pbj0EANOb/?igshid=x2wgie9r1cx3


Originally Posted by: Joe Bloggs 


I assume you are the manager?


Chunky Pea
12 March 2020 21:40:20


 Lots of events with more than 100 people!


Originally Posted by: xioni2 


Most supermarkets will have more than a hundred people in them at any one time panic buying bread and bog roll just in case the virus spreads.


 


 


Current Conditions
https://t.ly/MEYqg 


"You don't have to know anything to have an opinion"
--Roger P, 12/Oct/2022
Ulric
12 March 2020 21:41:01


Another question is what should you do if you contract it?


Presumably drink lots of water. I also assume eating as well as possible is advisable. More uncertain are things like cough medicine, aspirin, nurofen, paracetamol, codeine, nytol etc. I've not seen official guidance on off the shelf medicines such as these.


Originally Posted by: Brian Gaze 


Paracetomol is supposed to be helpful for the fever which apparently lasts 2 days. After that, I guess that anything which suppresses breathing, like codeine, is a no no.


"As soon as we abandon our own reason, and are content to rely on authority, there is no end to our troubles." - Bertrand Russell
https://postimg.cc/5XXnTCGn 
Arcus
12 March 2020 21:41:19


Hello Ben good news is most virus mutations are of negative value of the virus and the same vaccine can be used rather than explain I came across this a bit of a long read but interesting as the other day I wondered myself.


https://www.livescience.com/coronavirus-mutations.html


 


Originally Posted by: Polar Low 


Dangerous to extrapolate PL. This virus does not wear the clothes of it's predecessors in so many ways, and we've only just watched the opening credits on the film.


Ben,
Nr. Easingwold, North Yorkshire
30m asl
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